An MRI-informed histo-molecular analysis implicates ependymal cells in the pathogenesis of periventricular pathology in multiple sclerosis

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Adam M.R. Groh, Elia Afanasiev, Risavarshni Thevakumaran, Liam Callahan-Martin, Finn Creeggan, Moein Yaqubi, Stephanie Zandee, Alexandre Prat, David A. Rudko, Jo Anne Stratton

bioRxiv, Cold Spring Harbor Laboratory, 2026

Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis pathophysiology

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Maxime Bigotte, Adam M.R. Groh, Elia Afanasiev, Vincent Wong, Kevin Lancon, Moein Yaqubi, Finn Creeggan, Craig S. Moore, Adil Harroud, Raphael Schneider, Philippe S{\'e}gu{\'e}la, Marc Charabati, Fiona Tea, Antoine P. Fournier, Yu Chang Wang, Jiannis Ragoussis, Alexandre Prat, Simon Thebault, Stephanie Zandee, Jo Anne Stratton

bioRxiv, Cold Spring Harbor Laboratory, 2025

Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis

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Maxime Bigotte, Adam M R Groh, Elia Afanasiev, Vincent Wong, Kevin Lancon, Moein Yaqubi, Finn Creeggan, Airton Sinott, Junze Pei, Craig S Moore, Adil Harroud, Raphael Schneider, Philippe Séguéla, Marc Charabati, Fiona Tea, Antoine P Fournier, Yu Chang Wang, Jiannis Ragoussis, Alexandre Prat, Simon Thebault, Stephanie Zandee, Jo Anne Stratton

Brain, 2025 Nov, pp. awaf440

A subset of human choroid plexus epithelial cells exhibit mitochondrial eccentricity and distinct expression of the pigmentation-associated enzyme TYRP1

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Adam M.R. Groh, Shobina Premachandran, Finn Creeggan, Moein Yaqubi, Stephanie Zandee, Alexandre Prat, Jack P. Antel, G.R. Wayne Moore, Jo Anne Stratton

bioRxiv, Cold Spring Harbor Laboratory, 2024